摘要  　肾素血管紧张素系统(RA S)尤其是血管紧张素Ⅱ是促进血管重构的重要因素，而血管重构在心血管疾病的发生发展及病理演变中起着极为重要的作用阻断血管紧张素Ⅱ作用的任何环节均可影响心血管疾病的发生发展。本文就RA S对血管平滑肌增殖影响的最新进展作一综述。关键词  肾素血管紧张素系统   血管紧张素II  血管平滑肌  血管紧张素II受体1Abstract: 　The renin angiotensin system especially angiotensin Ⅱ is the important factors in promoting proliferation of vascular remodeling . .While vascular remodeling take s an important role in the incidence and development of cardiovascular disease. Blocking the actions of angiotensin II can affect and cure the cardiovascular disease. I will review the recent research on the relation between RAS and the proliferation of vascular smooth muscle.   1　肾素血管紧张素系统      RAS系统包括从血管紧张素原(AGT)生成AngⅡ的一系列酶促反应。AGT 由肝脏